Human dignity and worth are lost if we are merely products of chance and evolved from apes. We are cosmic accidents and do not know why we are here.
In contrast, we have dignity and great value if we are specially and purposely created by a personal God in His image and likeness. Furthermore, the fact that there is final accountability to our Creator means our lives (thoughts, actions) have meaning and are significant.
Finally, there is ultimate justice (righteousness will be rewarded, evil will be punished) and our destiny is not a mystery—there is life after death.